Author's response to reviews Title:Chlorophytum borivilianum (Safed Musli) root extract prevents impairment in characteristics and elevation of oxidative stress in sperm of streptozotocin-induced adult male diabetic Wistar rats Authors:

نویسندگان

  • Nelli Giribabu
  • Kilari Eswar Kumar
  • Somesula Swapna Rekha
  • Sekaran Muniandy
  • Naguib Salleh
چکیده

Title:Chlorophytum borivilianum (Safed Musli) root extract prevents impairment in characteristics and elevation of oxidative stress in sperm of streptozotocin-induced adult male diabetic Wistar rats

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Chlorophytum borivilianum (Safed Musli) root extract prevents impairment in characteristics and elevation of oxidative stress in sperm of streptozotocin-induced adult male diabetic Wistar rats

BACKGROUND We hypothesized that C. borivilianum root, known to improve male reproductive performance, prevents impairment in characteristics, morphology and elevation of oxidative stress in sperm of diabetics. We therefore investigated the effect of aqueous root extract of C. borivilianum on these parameters in diabetic rat model. METHODS C. borivilianum root aqueous extract (250 and 500 mg/k...

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Chlorophytum borivilianum Root Extract Maintains near Normal Blood Glucose, Insulin and Lipid Profile Levels and Prevents Oxidative Stress in the Pancreas of Streptozotocin-Induced Adult Male Diabetic Rats

UNLABELLED The effect of C. borivilianum root on blood glucose, glycated hemoglobin (HbAIc), insulin and lipid profile levels in diabetes mellitus are not fully understood. This study therefore investigated the effect of C. borivilianum root on the above parameters and oxidative stress of the pancreas in diabetes. METHODS C. borivilianum root aqueous extract (250 and 500 mg/kg/day) was admini...

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Modulatory Effect of Pioglitazone on Sperm Parameters and Oxidative Stress, Apoptotic and Inflammatory Biomarkers in Testes of Streptozotocin-Induced Diabetic Rats

Background and Aims: Diabetes mellitus causes testicular damage by increasing oxidative stress and inflammation. In the present study, modulation of oxidative stress by pioglitazone, a synthetic ligand of peroxisome proliferator-activated receptor-γ, was examined in testis of streptozotocin-induced diabetic rats. Materials and Methods: Diabetes was induced by a single dose of streptozot...

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تاریخ انتشار 2014